A comparison of the effects of contemporary dressings and 1% Povidone Iodine on the healing of diabetic ulceration: A Quasy Experiment

A comparison of the effects of contemporary dressings and 1% Povidone Iodine on the healing of diabetic ulceration: A Quasy Experiment

Authors

  • Indra Ariani STIKES Bina Husada
  • Dimas Putra Harsya STIKES Bina Husada
  • Asmat Burhan Universitas Harapan Bangsa

DOI:

https://doi.org/10.70196/jwrt.v1i1.4

Keywords:

modern dressing, povidone iodine1 %, wound care, wound healing

Abstract

Background: Diabetes ulcers are a consequence of diabetes mellitus (DM). Modern dressing techniques are essential for the treatment of diabetic ulcers, which are lesions that necessitate specific attention and control. The researchers set out to find out how a diabetic ulcer wound healing score changed after using a contemporary dressing.

Aims: Analyse the effectiveness of dressing and povidone iodine 1% on diabetic foot ulcer healing.

Design and Methods: Quasi experiment, pre-test and post-test of experiment group using modern dressing and control group using iodine. Total sampling technique was used in this study with a total of 84 patients. Data analysis was performed with a parametric test, namely paired t-test, and independent t-test.

Results: Both groups originally exhibited comparable wound diameters. On the 30th day, there was a decrease in wound size score (MD-CI) due to modern dressing. The drop was -1.94 with a 95% confidence interval of -4.37 to 0.14. The p-value was 0.043 and the r-squared value was -0.121. On the 60th day, the MD-CI treatment resulted in a reduction in wound size of -5.14 (95% confidence interval: -11.50 to -1.34; p=0.013; r2= -0.416).

Conclusion: At first, contemporary dressing therapy achieved a marginal reduction in lesion size. However, lesion size decreased substantially in diabetic foot ulcers after day 60. It is possible to suggest this intervention as a therapeutic approach for diabetic foot ulcers

References

Ahmed, S. F., Memon, I., Rajpar, Z. H., Asim, M., Anwar, A., & Elahi, W. (2019). Management of Fournier’s Gangrene; A Randomized Controlled Trial at High Volume Center Comparing the efficacy of Honey and Eusol Dressing in Wound Healing. Journal of Liaquat University of Medical & Health Sciences, 18(01), 06–11. https://doi.org/10.22442/jlumhs.191810593

Akin, T., Kendirci, M., Akgun, A. E., Ankara City Hospital, Ankara, Turkey, Cetinkaya, E., Ankara City Hospital, Ankara, Turkey, Er, S., Ankara City Hospital, Ankara, Turkey, Akin, M., & Ankara City Hospital, Ankara, Turkey. (2022). Applying a Silver-containing Dressing to the Incision Site and Its Effect on the Development of Surgical Site Infection After Ostomy Closure: A Prospective Randomized Clinical Pilot Study. Wound Management & Prevention, 68(4), 34–43. https://doi.org/10.25270/wmp.2022.4.3443

Akkus, G., & Sert, M. (2022). Diabetic foot ulcers: A devastating complication of diabetes mellitus continues non-stop in spite of new medical treatment modalities. World Journal of Diabetes, 13(12), 1106–1121. https://doi.org/10.4239/wjd.v13.i12.1106

Armstrong, D. G., Boulton, A. J. M., & Bus, S. A. (2017). Diabetic Foot Ulcers and Their Recurrence. New England Journal of Medicine, 376(24), 2367–2375. https://doi.org/10.1056/NEJMra1615439

Bagheri Miyab, K., Alipoor, E., Vaghardoost, R., Saberi Isfeedvajani, M., Yaseri, M., Djafarian, K., & Hosseinzadeh-Attar, M. J. (2020). The effect of a hydrolyzed collagen-based supplement on wound healing in patients with burn: A randomized double-blind pilot clinical trial. Burns, 46(1), 156–163. https://doi.org/10.1016/j.burns.2019.02.015

Burhan, A., Ali Khusein, N. bin, & Sebayang, S. M. (2022). Effectiveness of negative pressure wound therapy on chronic wound healing: A systematic review and meta-analysis. Belitung Nursing Journal, 8(6), 470–480. https://doi.org/10.33546/bnj.2220

Burhan, A., & Arofiati, F. (2021). Effect of Compression Bandage on the Healing of Diabetic Foot Ulcers: A Scooping Review: 4th International Conference on Sustainable Innovation 2020–Health Science and Nursing (ICoSIHSN 2020), Yogyakarta, Indonesia. https://doi.org/10.2991/ahsr.k.210115.110

Burhan, A., Arofiati, F., Abreu Da Silva, V., & Mixrova Sebayang, S. (2023). Effect of ankle brachial index (abi) and compression therapy on diabetic foot ulcer healing. Current Diabetes Reviews, 19. https://doi.org/10.2174/1573399819666230331083420

Burhan, A., & Sebayang, S. M. (2022). The Combination of Polyhexamethylene Biguanide and Cadexomer Iodine in Healing Chronic Venous Leg Ulcers: A Case Report. Viva Medika: Jurnal Kesehatan, Kebidanan Dan Keperawatan, 16(1), 12–21. https://doi.org/10.35960/vm.v16i1.832

Crocker, R. M., Palmer, K. N. B., Marrero, D. G., & Tan, T.-W. (2021). Patient perspectives on the physical, psycho-social, and financial impacts of diabetic foot ulceration and amputation. Journal of Diabetes and Its Complications, 35(8), 107960. https://doi.org/10.1016/j.jdiacomp.2021.107960

Everett, E., & Mathioudakis, N. (2018). Update on management of diabetic foot ulcers: Diabetic foot ulcers. Annals of the New York Academy of Sciences, 1411(1), 153–165. https://doi.org/10.1111/nyas.13569

Fedorko, L., Bowen, J. M., Jones, W., Oreopoulos, G., Goeree, R., Hopkins, R. B., & O’Reilly, D. J. (2016). Hyperbaric Oxygen Therapy Does Not Reduce Indications for Amputation in Patients With Diabetes With Nonhealing Ulcers of the Lower Limb: A Prospective, Double-Blind, Randomized Controlled Clinical Trial. Diabetes Care, 39(3), 392–399. https://doi.org/10.2337/dc15-2001

Gould, L., Abadir, P., Brem, H., Carter, M., Conner-Kerr, T., Davidson, J., DiPietro, L., Falanga, V., Fife, C., Gardner, S., Grice, E., Harmon, J., Hazzard, W. R., High, K. P., Houghton, P., Jacobson, N., Kirsner, R. S., Kovacs, E. J., Margolis, D., … Schmader, K. (2015). Chronic Wound Repair and Healing in Older Adults: Current Status and Future Research. Journal of the American Geriatrics Society, 63(3), 427–438. https://doi.org/10.1111/jgs.13332

Izadi, M., Kheirjou, R., Mohammadpour, R., Aliyoldashi, M. H., Moghadam, S. J., Khorvash, F., Jafari, N. J., Shirvani, S., & Khalili, N. (2019). Efficacy of comprehensive ozone therapy in diabetic foot ulcer healing. Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13(1), 822–825. https://doi.org/10.1016/j.dsx.2018.11.060

Jamovi. (2023). The jamovi project (2.3) [English]. Jamovi. https://www.jamovi.org

Jeong, S.-H., Han, S.-K., & Kim, W.-K. (2010). Treatment of Diabetic Foot Ulcers Using a Blood Bank Platelet Concentrate: Plastic and Reconstructive Surgery, 125(3), 944–952. https://doi.org/10.1097/PRS.0b013e3181cb6589

Jiang, P., Li, Q., Luo, Y., Luo, F., Che, Q., Lu, Z., Yang, S., Yang, Y., Chen, X., & Cai, Y. (2023). Current status and progress in research on dressing management for diabetic foot ulcer. Frontiers in Endocrinology, 14, 1221705. https://doi.org/10.3389/fendo.2023.1221705

Lim, S., Bae, J. H., Kwon, H.-S., & Nauck, M. A. (2021). COVID-19 and diabetes mellitus: From pathophysiology to clinical management. Nature Reviews Endocrinology, 17(1), 11–30. https://doi.org/10.1038/s41574-020-00435-4

Lindholm, C., & Searle, R. (2016). Wound management for the 21st century: Combining effectiveness and efficiency. International Wound Journal, 13(S2), 5–15. https://doi.org/10.1111/iwj.12623

Marks, D., Shah, M., Patkar, A., Masand, P., Park, G.-Y., & Pae, C.-U. (2009). Serotonin-Norepinephrine Reuptake Inhibitors for Pain Control: Premise and Promise. Current Neuropharmacology, 7(4), 331–336. https://doi.org/10.2174/157015909790031201

Ministry of Heallth RI. (2018). Hasil Utama Riskesdas 2018. Kementrian Kesehatan RI. https://kesmas.kemkes.go.id/assets/upload/dir_519d41d8cd98f00/files/Hasil-riskesdas-2018_1274.pdf

Mohammadi, R., Javanmard, G. H., Alipour, A., & Zare, H. (2022). Effects of mindful breath awareness and muscle relaxation and transcranial electrical stimulation techniques on improving blood pressure status in patients with type 2 diabetes. EXPLORE, 18(2), 200–204. https://doi.org/10.1016/j.explore.2021.05.002

Rousselle, P., Braye, F., & Dayan, G. (2019). Re-epithelialization of adult skin wounds: Cellular mechanisms and therapeutic strategies. Advanced Drug Delivery Reviews, 146, 344–365. https://doi.org/10.1016/j.addr.2018.06.019

Sapra, A., & Bhandari, P. (2022). Diabetes Mellitus. StatPearls Publishing, Treasure Island (FL). https://www.ncbi.nlm.nih.gov/books/NBK551501/

Seidel, D., Storck, M., Lawall, H., Wozniak, G., Mauckner, P., Hochlenert, D., Wetzel-Roth, W., Sondern, K., Hahn, M., Rothenaicher, G., Krönert, T., Zink, K., & Neugebauer, E. (2020). Negative pressure wound therapy compared with standard moist wound care on diabetic foot ulcers in real-life clinical practice: Results of the German DiaFu-RCT. BMJ Open, 10(3), e026345. https://doi.org/10.1136/bmjopen-2018-026345

Verdolino, D. V., Thomason, H. A., Fotticchia, A., & Cartmell, S. (2021). Wound dressings: Curbing inflammation in chronic wound healing. Emerging Topics in Life Sciences, 5(4), 523–537. https://doi.org/10.1042/ETLS20200346

Zhang, P., Lu, J., Jing, Y., Tang, S., Zhu, D., & Bi, Y. (2017). Global epidemiology of diabetic foot ulceration: A systematic review and meta-analysis. Annals of Medicine, 49(2), 106–116. https://doi.org/10.1080/07853890.2016.1231932

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Published

2024-04-28

How to Cite

Ariani, I., Putra Harsya, D., & Burhan, A. (2024). A comparison of the effects of contemporary dressings and 1% Povidone Iodine on the healing of diabetic ulceration: A Quasy Experiment. Journal of Wound Research and Technology , 1(1), 19–27. https://doi.org/10.70196/jwrt.v1i1.4

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